HPE ProLiant ML350 Gen11 Tower with 2x NVIDIA L40S
Office-quiet tower with dual L40S for on-prem and edge AI.
We help you choose, configure, and deliver the right system — no obligation.
Configuration at a Glance
Tailored per engagement. Full technical overview below.
Configuration Options
Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.
2x NVIDIA L40S 48GB
1-2x Intel Xeon Scalable (4th/5th Gen), up to 64 cores per socket
Up to 8TB DDR5 (32 DIMM slots, dual-socket)
SFF/EDSFF hot-plug bays with HPE Smart Array; NS204i boot option
Overview
The ML350 Gen11 is a 4U tower configured with two NVIDIA L40S accelerators for inference, design, and analytics outside the data center. Each unit is built to specification, tested for acoustic and thermal behavior, and supplied with HPE warranty through authorized distribution.
Who This Solution Is For
Business Benefits
Deploys anywhere
Tower form factor and low acoustics let it run in offices and labs without dedicated data-center cooling.
Practical AI acceleration
Two L40S GPUs deliver capable inference and visualization performance for on-prem and edge workloads.
Room to grow
Generous PCIe Gen5 slots and DDR5 capacity let the tower scale as workloads expand.
Typical Business Use Cases
On-prem AI inference and fine-tuning
3D rendering and visualization
Edge and branch analytics
Departmental virtualization
Industry Applications
Technical Overview
The ML350 Gen11 4U tower runs 4th/5th Gen Intel Xeon Scalable processors with up to 8TB DDR5 and up to ten PCIe Gen5 slots. Two NVIDIA L40S accelerators are installed within the platform's supported GPU envelope, with iLO 6 providing secure remote management even at unstaffed sites.
| GPU/Accelerator | 2x NVIDIA L40S 48GB |
| CPU | 1-2x Intel Xeon Scalable (4th/5th Gen), up to 64 cores per socket |
| Memory | Up to 8TB DDR5 (32 DIMM slots, dual-socket) |
| Storage | SFF/EDSFF hot-plug bays with HPE Smart Array; NS204i boot option |
| Networking | OCP 3.0 plus PCIe Gen5 adapters (up to 25/100GbE) |
| Form Factor | 4U tower (rack-convertible) |
| Management | HPE iLO 6 with Silicon Root of Trust |
| Power | Redundant hot-plug power supply options |
| Warranty | HPE limited warranty via authorized channel; support upgrades available |
Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.
Warranty, Support & Fulfillment
Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.
Enterprise Warranty
Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.
Authorized Channel
Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.
Lead Time & Deployment
48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.
Nationwide Fulfillment
Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.
Frequently Asked Questions
Can the ML350 Gen11 run in an office environment?
Yes — its tower chassis and tuned acoustics are designed for office and lab settings, removing the need for a data-center rack.
How many GPUs does the ML350 Gen11 support?
Depending on chassis and power configuration the platform supports multiple accelerators; this build uses two L40S cards within HPE's validated limits.
Is it suitable for edge deployment?
It is well suited to edge and branch sites, with iLO 6 enabling secure remote setup, monitoring, and updates from a central team.
Hardware Assistance
Configure the HPE ProLiant ML350 Gen11 Tower with 2x NVIDIA L40S with Nexus Compute
Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.