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HPE ProLiant DL385

AMD EPYC performance and core density in a versatile 2U platform.

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We help you choose, source, and procure the right infrastructure — no obligation.

Configuration at a Glance

Form Factor2U rackmount

CPUAMD EPYC (single or dual socket)

MemoryUp to 8TB (generation-dependent)

StorageNVMe / SAS / SATA (configurable)

Tailored per engagement. Full technical overview below.

Overview

The HPE ProLiant DL385 brings AMD EPYC processors to HPE's proven 2U platform, delivering exceptional core counts and memory bandwidth per server. Nexus Compute sources DL385 systems for workloads that benefit from EPYC's density and value — virtualization, analytics, and core-hungry applications.

Who This Solution Is For

Teams running core-dense virtualization or VDI

Analytics and HPC-adjacent workloads

Organizations optimizing per-core licensing economics

IT teams favoring AMD EPYC price-performance

Business Benefits

Exceptional core density

High EPYC core counts host more VMs or threads per server, improving consolidation ratios.

Strong memory bandwidth

EPYC's memory architecture benefits analytics and bandwidth-sensitive workloads.

Licensing efficiency

For some per-socket licensed software, high-core single sockets can reduce license costs.

HPE management and support

EPYC performance with the familiar iLO and OneView ecosystem.

Typical Business Use Cases

Core-dense virtualization and VDI

Analytics and in-memory workloads

Containerized platforms needing high thread counts

General compute favoring AMD EPYC value

Industry Applications

Financial ServicesEducation & ResearchSoftware & SaaSHealthcare & Life Sciences

Technical Overview

A 2U platform built on AMD EPYC processors with high core counts, large DDR memory capacity, flexible storage, iLO management, and redundant power.

Form Factor	2U rackmount
CPU	AMD EPYC (single or dual socket)
Memory	Up to 8TB (generation-dependent)
Storage	NVMe / SAS / SATA (configurable)
Management	HPE iLO + OneView
Security	AMD Infinity Guard features
Power	Redundant PSUs (N+1)
Warranty	HPE support (configurable)

Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.

Frequently Asked Questions

AMD EPYC or Intel Xeon — how do we decide?

EPYC typically wins on core density, memory bandwidth, and per-core value; Xeon can lead on certain single-thread and Intel-specific features. We advise based on your workload and software.

Does EPYC affect software compatibility?

Modern enterprise software runs on EPYC without issue. For specific certified applications we confirm support during the quote.

Can it reduce our licensing costs?

In some per-socket licensing scenarios, high-core single-socket EPYC configurations reduce license counts. We help model this.

Procurement Assistance

Source the HPE ProLiant DL385 with Nexus Compute

Tell us your requirements and a procurement specialist will help you specify, source, and quote the right configuration — typically within two business days. No obligation.

Request Quote Speak to an Infrastructure Specialist