HPE ProLiant DL580 Gen11 4-Socket Server with 3x NVIDIA H100
Scale-up CPU and triple H100 acceleration in one 4U chassis.
We help you choose, configure, and deliver the right system — no obligation.




Configuration at a Glance
Tailored per engagement. Full technical overview below.
Configuration Options
Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.
3x NVIDIA H100 80GB PCIe (double-wide)
4x Intel Xeon Scalable (4th/5th Gen), up to 64 cores per socket
Up to 6TB DDR5 across 48 DIMM slots
SFF NVMe hot-plug bays with HPE Smart Array / NS204i boot
Overview
This DL580 Gen11 pairs four Intel Xeon sockets with three NVIDIA H100 PCIe accelerators for memory-bound HPC and mixed CPU/GPU simulation. It is assembled to specification, thermally validated for the GPU thermal envelope, and supplied with HPE warranty through authorized channels.
Who This Solution Is For
Business Benefits
Balanced CPU-GPU compute
Four sockets feed three H100 accelerators so memory-heavy preprocessing never starves the GPUs.
Dense acceleration
Three double-wide GPUs in a single 4U node cut rack space and interconnect complexity for hybrid workloads.
Enterprise-grade reliability
HPE RAS, redundant cooling, and iLO 6 telemetry keep long-running simulation jobs stable.
Typical Business Use Cases
Computational fluid dynamics and CAE
Quantitative risk simulation
Scientific HPC with large working sets
Mixed CPU/GPU modeling pipelines
Industry Applications
Technical Overview
The DL580 Gen11 4U platform hosts four 4th/5th Gen Intel Xeon Scalable processors plus three NVIDIA H100 PCIe Gen5 accelerators within its supported double-wide GPU envelope. High DDR5 capacity and PCIe Gen5 lanes provide the host bandwidth required to keep the accelerators fed, managed end-to-end by HPE iLO 6.
| GPU/Accelerator | 3x NVIDIA H100 80GB PCIe (double-wide) |
| GPU Interconnect | PCIe Gen5; optional NVLink Bridge on paired cards |
| CPU | 4x Intel Xeon Scalable (4th/5th Gen), up to 64 cores per socket |
| Memory | Up to 6TB DDR5 across 48 DIMM slots |
| Storage | SFF NVMe hot-plug bays with HPE Smart Array / NS204i boot |
| Networking | OCP 3.0 plus PCIe Gen5 NICs up to 200Gb InfiniBand/Ethernet |
| Form Factor | 4U rack, 4-socket |
| Management | HPE iLO 6 with Silicon Root of Trust |
| Warranty | HPE limited warranty via authorized channel; on-site support upgrades available |
Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.
Warranty, Support & Fulfillment
Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.
Enterprise Warranty
Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.
Authorized Channel
Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.
Lead Time & Deployment
48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.
Nationwide Fulfillment
Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.
Frequently Asked Questions
Why choose a 4-socket host for only three GPUs?
Memory-bound HPC and simulation codes benefit from the large DDR5 capacity and core count of four sockets to prepare data and run CPU-side phases alongside GPU acceleration.
How many H100s does the DL580 Gen11 support?
The platform supports double-wide GPUs within its validated thermal and power envelope; we configure and test the three-H100 build to HPE's supported limits.
Can I add high-speed fabric for a cluster?
Yes — PCIe Gen5 slots accept 200Gb InfiniBand or Ethernet adapters so nodes can be clustered for distributed HPC jobs.
Hardware Assistance
Configure the HPE ProLiant DL580 Gen11 4-Socket Server with 3x NVIDIA H100 with Nexus Compute
Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.