HPE ProLiant DL385 Gen11 with 2x NVIDIA L40S (EPYC)
AMD EPYC plus dual L40S for visual computing and fine-tuning.
We help you choose, configure, and deliver the right system — no obligation.
Configuration at a Glance
Tailored per engagement. Full technical overview below.
Configuration Options
Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.
2x NVIDIA L40S (48GB GDDR6 each)
AMD EPYC 9004 (single or dual socket)
DDR5, up to 6TB (configurable)
NVMe / SAS / SATA (configurable)
Overview
This HPE ProLiant DL385 Gen11 configuration combines high-core-count AMD EPYC processors with two NVIDIA L40S GPUs for generative AI, fine-tuning, and visual-computing workloads. The system is specified, configured, and validated before delivery, carrying HPE warranty coverage and sourced through authorized channels.
Who This Solution Is For
Business Benefits
Balanced AI and graphics
Dual L40S GPUs handle both generative AI and rendering, serving mixed creative and ML pipelines from one node.
High CPU core density
AMD EPYC's core counts feed GPU pipelines and run data-prep stages without becoming a bottleneck.
Versatile expansion
The 2U DL385 chassis offers generous storage and PCIe headroom for evolving workloads.
Typical Business Use Cases
Generative AI image and video workloads
Model fine-tuning and inference
3D rendering and virtual workstation hosting
Mixed AI and visualization pipelines
Industry Applications
Technical Overview
The DL385 Gen11 pairs single or dual 4th Gen AMD EPYC processors with up to two double-wide NVIDIA L40S GPUs on PCIe Gen5, backed by DDR5 memory. Each L40S provides 48GB GDDR6 with RT and Tensor cores, and iLO 6 manages the platform with a silicon root of trust.
| GPU / Accelerator | 2x NVIDIA L40S (48GB GDDR6 each) |
| GPU Interconnect | PCIe Gen5 (no NVLink on L40S) |
| CPU | AMD EPYC 9004 (single or dual socket) |
| Memory | DDR5, up to 6TB (configurable) |
| Storage | NVMe / SAS / SATA (configurable) |
| Networking | OCP 3.0 + PCIe Gen5, up to 100GbE |
| Form Factor | 2U rackmount |
| Management | HPE iLO 6 + OneView |
| Warranty | HPE support (configurable) |
Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.
Warranty, Support & Fulfillment
Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.
Enterprise Warranty
Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.
Authorized Channel
Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.
Lead Time & Deployment
48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.
Nationwide Fulfillment
Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.
Frequently Asked Questions
Why pair L40S with EPYC?
L40S covers generative AI and graphics in one GPU, while EPYC's high core counts feed those GPUs and accelerate CPU-bound data preparation, making the pairing efficient for mixed pipelines.
Is the L40S good for both AI and rendering?
Yes; the L40S includes Tensor cores for AI and RT cores for rendering, so a single node serves fine-tuning, inference, and visual workloads.
EPYC or Xeon for this role?
We recommend EPYC where core density and memory bandwidth matter most; we will model your licensing and workload to confirm the right CPU choice.
Hardware Assistance
Configure the HPE ProLiant DL385 Gen11 with 2x NVIDIA L40S (EPYC) with Nexus Compute
Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.