HPE ProLiant DL380 Gen11 with 2x NVIDIA H100 NVL
Versatile 2U GPU node for LLM inference and fine-tuning.
We help you choose, configure, and deliver the right system — no obligation.
Configuration at a Glance
Tailored per engagement. Full technical overview below.
Configuration Options
Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.
2x NVIDIA H100 NVL (94GB HBM3 each)
Dual Intel Xeon Scalable (4th/5th Gen)
DDR5, up to 8TB (configurable)
NVMe Gen5 SFF (configurable)
Overview
This HPE ProLiant DL380 Gen11 configuration adds two NVLink-bridged NVIDIA H100 NVL GPUs to HPE's flagship 2U platform for large-language-model inference and fine-tuning. The system is configured, thermally validated, and tested as a unit before delivery, carrying HPE warranty coverage sourced through authorized channels.
Who This Solution Is For
Business Benefits
Large-model capacity
Two NVL-bridged H100s pool 188GB of HBM3 to hold sizable models entirely in GPU memory.
Flexible 2U platform
The DL380 chassis balances GPU acceleration with ample storage and PCIe expansion in one node.
Familiar HPE operations
iLO 6 and OneView fold GPU compute into existing management and lifecycle workflows.
Typical Business Use Cases
On-premises LLM inference serving
Parameter-efficient fine-tuning
Retrieval-augmented generation backends
GPU-accelerated analytics
Industry Applications
Technical Overview
The DL380 Gen11 accepts two double-wide NVIDIA H100 NVL GPUs joined by an NVLink bridge on a dual-socket 4th/5th Gen Intel Xeon Scalable base with DDR5 memory and PCIe Gen5. Each H100 NVL provides 94GB HBM3, and iLO 6 secures the platform with a silicon root of trust.
| GPU / Accelerator | 2x NVIDIA H100 NVL (94GB HBM3 each) |
| GPU Interconnect | NVLink bridge between paired GPUs |
| CPU | Dual Intel Xeon Scalable (4th/5th Gen) |
| Memory | DDR5, up to 8TB (configurable) |
| Storage | NVMe Gen5 SFF (configurable) |
| Networking | OCP 3.0 + PCIe Gen5, up to 200GbE |
| Form Factor | 2U rackmount |
| Management | HPE iLO 6 + OneView |
| Warranty | HPE support (configurable) |
Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.
Warranty, Support & Fulfillment
Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.
Enterprise Warranty
Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.
Authorized Channel
Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.
Lead Time & Deployment
48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.
Nationwide Fulfillment
Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.
Frequently Asked Questions
How large a model can two H100 NVL GPUs serve?
With 188GB of pooled HBM3 across the NVLink bridge the pair can hold many tens-of-billions-parameter models in memory; we validate the exact fit against your target models.
DL380 with GPUs or the DL380a — which should we pick?
The DL380 suits two-GPU inference and mixed workloads, while the purpose-built DL380a scales to four GPUs for training; we recommend based on your GPU count and workload.
Can it deploy in a standard rack?
Yes, in a 2U slot; we confirm power and airflow requirements for the dual-H100 configuration during planning.
Hardware Assistance
Configure the HPE ProLiant DL380 Gen11 with 2x NVIDIA H100 NVL with Nexus Compute
Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.