Skip to content
HomeSolutionsHPEHPE Cray XD675 (8x AMD Instinct MI300X OAM, Dual 4th Gen AMD EPYC)
HPE logo
HPENew

HPE Cray XD675 (8x AMD Instinct MI300X OAM, Dual 4th Gen AMD EPYC)

1.5TB of HBM3 across eight MI300X for memory-bound AI and HPC.

Full manufacturer warrantyAuthorized channel48-hour quote

We help you choose, configure, and deliver the right system — no obligation.

HPE Cray XD675 (8x AMD Instinct MI300X OAM, Dual 4th Gen AMD EPYC) — HPE enterprise hardware
HPE logo
HPE Cray XD675 (8x AMD Instinct MI300X OAM, Dual 4th Gen AMD EPYC) hardware detail 1
HPE Cray XD675 (8x AMD Instinct MI300X OAM, Dual 4th Gen AMD EPYC) hardware detail 2
HPE Cray XD675 (8x AMD Instinct MI300X OAM, Dual 4th Gen AMD EPYC) hardware detail 3

Configuration at a Glance

GPU / Accelerator8x AMD Instinct MI300X OAM, 192GB HBM3 each (1.5TB total)
GPU InterconnectAMD Infinity Fabric (OAM baseboard)
CPUDual 4th Gen AMD EPYC (Genoa), up to 400W TDP
MemoryUp to 24x DDR5-5600 DIMMs

Tailored per engagement. Full technical overview below.

Configuration Options

Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.

GPU / Accelerator

8x AMD Instinct MI300X OAM, 192GB HBM3 each (1.5TB total)

Processor

Dual 4th Gen AMD EPYC (Genoa), up to 400W TDP

Memory

Up to 24x DDR5-5600 DIMMs

Storage

Up to 16x SFF NVMe SSDs + 2x M.2

Overview

The HPE Cray XD675 in this configuration hosts eight AMD Instinct MI300X OAM accelerators with dual 4th Gen AMD EPYC processors, delivering 1.5TB of GPU memory in a single node. Nexus Compute provides it specified, integrated, and tested on the ROCm stack with direct liquid cooling and HPE warranty through authorized channels.

Who This Solution Is For

Teams running memory-hungry LLM inference and training
HPC sites adopting the AMD Instinct and ROCm stack
Organizations seeking an alternative GPU supply chain
Researchers needing maximum HBM per server

Business Benefits

Massive GPU memory

1.5TB of HBM3 across eight MI300X lets very large models load and serve with less sharding overhead.

Open ROCm software

The AMD ROCm ecosystem offers an open, portable path for AI and HPC codebases.

Supply diversification

An AMD Instinct platform broadens accelerator sourcing options beyond a single vendor.

Typical Business Use Cases

1

Large-model LLM inference and serving

2

Memory-bound AI training

3

FP64-intensive HPC simulation

4

Mixed AI and scientific computing workloads

Industry Applications

AI & Machine LearningHPCHigher Education & ResearchGovernment & DefenseHealthcare & Life Sciences

Technical Overview

The XD675 carries an eight-way AMD Instinct MI300X OAM baseboard with Infinity Fabric GPU links, dual 4th Gen AMD EPYC Genoa CPUs, and up to 24 DDR5-5600 DIMMs. The chassis supports direct liquid cooling and eight PCIe Gen5 fabric slots for InfiniBand NDR or Ethernet, delivering roughly 10.4 PFLOPs peak FP16 per server.

GPU / Accelerator8x AMD Instinct MI300X OAM, 192GB HBM3 each (1.5TB total)
GPU InterconnectAMD Infinity Fabric (OAM baseboard)
CPUDual 4th Gen AMD EPYC (Genoa), up to 400W TDP
MemoryUp to 24x DDR5-5600 DIMMs
StorageUp to 16x SFF NVMe SSDs + 2x M.2
Networking / Fabric8x PCIe Gen5: InfiniBand NDR / Ethernet
Form Factor5U GPU node
CoolingDirect liquid cooling
WarrantyHPE support, configurable terms

Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.

Warranty, Support & Fulfillment

Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.

Enterprise Warranty

Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.

Authorized Channel

Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.

Lead Time & Deployment

48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.

Nationwide Fulfillment

Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.

Frequently Asked Questions

When does MI300X beat an NVIDIA node for our workload?

MI300X shines on memory-bound jobs: 192GB per GPU and 1.5TB per node let large models fit with minimal sharding, which can simplify serving and improve throughput. We assess your models and software to confirm fit.

Will our existing code run on ROCm?

Major frameworks like PyTorch and many HPC libraries support ROCm, and AMD provides HIP tooling to port CUDA code. We help validate your stack before deployment.

Is the XD675 suited to double-precision HPC?

Yes. MI300X delivers strong FP64 performance, making this node effective for scientific simulation as well as AI. We tune the configuration to your balance of AI and HPC work.

Hardware Assistance

Configure the HPE Cray XD675 (8x AMD Instinct MI300X OAM, Dual 4th Gen AMD EPYC) with Nexus Compute

Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.