Supermicro BigTwin SYS-221BT-HNTR (2U 4-Node Intel Xeon)
Four independent Xeon nodes in 2U for high-density virtualization and HCI.
We help you choose, configure, and deliver the right system — no obligation.




Configuration at a Glance
Tailored per engagement. Full technical overview below.
Configuration Options
Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.
1x PCIe 5.0 x16 LP per node
Dual 5th/4th Gen Intel Xeon Scalable per node
16 DIMM slots per node, up to 4TB DDR5-5600 ECC
6x hot-swap 2.5" NVMe/SAS per node + M.2 boot
Overview
The BigTwin SYS-221BT-HNTR packs four hot-pluggable dual-Xeon nodes into a shared 2U enclosure, maximizing compute density per rack while keeping each node independently serviceable. Nexus Compute configures and validates the full enclosure to your virtualization or hyperconverged design, sourced through authorized Supermicro channels with manufacturer warranty.
Who This Solution Is For
Business Benefits
Four nodes per 2U
Shared power and cooling deliver dense compute that lowers rack, power, and cooling cost per node.
Independent serviceability
Each node hot-plugs from the rear, so one server can be serviced without disturbing the other three.
Efficient shared power
Shared Titanium-level PSUs improve power efficiency versus four discrete 1U servers.
Typical Business Use Cases
Hyperconverged infrastructure clusters
High-density server virtualization
Virtual desktop infrastructure at scale
Private cloud compute pools
Industry Applications
Technical Overview
The X13 BigTwin places four independent nodes in a 2U chassis, each with dual Socket E (LGA-4677) Xeon CPUs, 16 DDR5 DIMM slots, and six hot-swap NVMe/SAS bays. A shared cooling and 3000W Titanium redundant power design maximizes density and efficiency across the enclosure.
| Form Factor | 2U enclosure, 4 hot-pluggable nodes |
| CPU | Dual 5th/4th Gen Intel Xeon Scalable per node |
| Memory | 16 DIMM slots per node, up to 4TB DDR5-5600 ECC |
| Storage | 6x hot-swap 2.5" NVMe/SAS per node + M.2 boot |
| Networking/Fabric | AIOM (OCP NIC 3.0) per node; 25/100GbE |
| GPU Interconnect | 1x PCIe 5.0 x16 LP per node |
| Management | IPMI 2.0 / Redfish per node |
| Power | Shared 3000W Titanium redundant PSUs |
| Warranty | Manufacturer-backed, authorized channel |
Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.
Warranty, Support & Fulfillment
Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.
Enterprise Warranty
Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.
Authorized Channel
Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.
Lead Time & Deployment
48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.
Nationwide Fulfillment
Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.
Frequently Asked Questions
Can nodes be configured differently?
Nodes in a BigTwin share a chassis but each is an independent server. We typically configure them identically for cluster uniformity, and can advise where mixed builds make sense.
Why choose BigTwin over four 1U servers?
BigTwin delivers the same four-node compute in 2U with shared, more efficient power and cooling, reducing rack space and operating cost while keeping each node serviceable.
Is it suited to hyperconverged software?
Yes. With per-node NVMe and high-speed networking it is a strong building block for VMware vSAN, Nutanix, and similar HCI stacks. We validate the configuration to your platform.
Hardware Assistance
Configure the Supermicro BigTwin SYS-221BT-HNTR (2U 4-Node Intel Xeon) with Nexus Compute
Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.