Supermicro SYS-521GE-TNRT 8x NVIDIA L40S 48GB Inference Server
Eight L40S GPUs in 5U for high-throughput inference and fine-tuning.
We help you choose, configure, and deliver the right system — no obligation.




Configuration at a Glance
Tailored per engagement. Full technical overview below.
Configuration Options
Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.
8x NVIDIA L40S 48GB GDDR6 (Ada Lovelace, 350W)
Dual Intel Xeon 5th Gen Scalable, up to 64 cores each
Up to 8TB DDR5-5600 ECC (32 DIMM slots)
Up to 24x 2.5" hot-swap NVMe/SATA
Overview
This 5U platform pairs eight NVIDIA L40S 48GB Ada Lovelace GPUs with dual 5th Gen Intel Xeon processors to deliver dense FP8 inference and parameter-efficient fine-tuning in one node. Nexus Compute specifies, integrates, and burn-in tests the complete system, then delivers it warranty-backed through authorized supply channels.
Who This Solution Is For
Business Benefits
Maximum inference density
Eight 48GB GPUs serve large batches and multiple models concurrently from a single 5U chassis.
FP8 cost efficiency
The L40S Transformer Engine delivers high tokens-per-watt for inference without HBM-class capital cost.
Tested before delivery
We validate multi-GPU thermals, firmware, and drivers so the node is production-stable on arrival.
Typical Business Use Cases
Concurrent multi-model LLM inference serving
LoRA and QLoRA fine-tuning of mid-size models
Batch embedding and retrieval pipelines
Mixed AI plus visual-compute workloads
Industry Applications
Technical Overview
Built on the Supermicro SYS-521GE-TNRT 5U dual-root PCIe platform with 13 PCIe Gen5 x16 slots and 32 DDR5 DIMM slots across two Socket E (LGA-4677) CPUs. Eight L40S GPUs connect over PCIe Gen4 x16 within a dual-root topology engineered for balanced GPU-to-CPU bandwidth.
| GPU | 8x NVIDIA L40S 48GB GDDR6 (Ada Lovelace, 350W) |
| GPU Interconnect | PCIe Gen5 dual-root; optional NVLink Bridge pairs |
| CPU | Dual Intel Xeon 5th Gen Scalable, up to 64 cores each |
| Memory | Up to 8TB DDR5-5600 ECC (32 DIMM slots) |
| Storage | Up to 24x 2.5" hot-swap NVMe/SATA |
| Networking | Dual 10GbE onboard; AIOM/OCP 3.0 for 100/400GbE |
| Form Factor | 5U rackmount |
| Power | 4x 2700W (2+2) redundant Titanium PSUs |
| Warranty | Manufacturer-backed; extended options available |
Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.
Warranty, Support & Fulfillment
Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.
Enterprise Warranty
Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.
Authorized Channel
Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.
Lead Time & Deployment
48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.
Nationwide Fulfillment
Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.
Frequently Asked Questions
How many models can eight L40S GPUs serve at once?
It depends on model size and quantization, but 384GB of aggregate GPU memory comfortably hosts several quantized mid-size LLMs or many smaller models concurrently. We size the configuration to your serving targets during specification.
Is the L40S a good fit for fine-tuning rather than full training?
Yes. The L40S excels at parameter-efficient methods like LoRA and QLoRA and at fine-tuning mid-size models; for large-scale pretraining we would recommend an HBM SXM platform instead.
What facility power and cooling does this 5U node require?
With four 2700W Titanium PSUs it belongs in a data center or properly provisioned server room; we confirm exact power, cooling, and rack requirements before delivery.
Hardware Assistance
Configure the Supermicro SYS-521GE-TNRT 8x NVIDIA L40S 48GB Inference Server with Nexus Compute
Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.