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Supermicro AS-8125GS-TNMR2 — 8x MI300X Liquid-Cooled (EPYC 9004)

Direct-liquid-cooled 8-GPU MI300X density for sustained large-scale training.

Full manufacturer warrantyAuthorized channel48-hour quote

We help you choose, configure, and deliver the right system — no obligation.

Supermicro AS-8125GS-TNMR2 — 8x MI300X Liquid-Cooled (EPYC 9004) — Nexus Compute enterprise hardware
Supermicro AS-8125GS-TNMR2 — 8x MI300X Liquid-Cooled (EPYC 9004) hardware detail 1
Supermicro AS-8125GS-TNMR2 — 8x MI300X Liquid-Cooled (EPYC 9004) hardware detail 2
Supermicro AS-8125GS-TNMR2 — 8x MI300X Liquid-Cooled (EPYC 9004) hardware detail 3

Configuration at a Glance

Accelerator8x AMD Instinct MI300X OAM, 192GB HBM3 each (1.5TB total)
GPU InterconnectAMD Infinity Fabric, all-to-all (6.4TB/s bisection)
CPUDual AMD EPYC 9004 (Genoa)
System MemoryUp to 6TB DDR5 (24 DIMM slots)

Tailored per engagement. Full technical overview below.

Configuration Options

Core specifications for this system. Every component is configurable to your workload — request a quote for a tailored build.

GPU / Accelerator

8x AMD Instinct MI300X OAM, 192GB HBM3 each (1.5TB total)

Processor

Dual AMD EPYC 9004 (Genoa)

Memory

Up to 6TB DDR5 (24 DIMM slots)

Storage

16x hot-swap NVMe + 2x SATA + 2x M.2 NVMe

Overview

The Supermicro AS-8125GS-TNMR2 packs eight MI300X OAM accelerators and dual AMD EPYC processors into an 8U chassis with direct-to-chip liquid cooling for uninterrupted, high-clock training. Nexus Compute configures the cooling loop, 1:1 GPU-to-NIC fabric, and ROCm stack, then validates thermals before warranty-backed delivery through authorized channels.

Who This Solution Is For

AI labs running continuous multi-day training jobs
Operators of liquid-ready, high-density data centers
Teams maximizing sustained clocks under heavy thermal load
All-AMD shops pairing EPYC hosts with Instinct accelerators

Business Benefits

Sustained training performance

Direct-to-chip liquid cooling holds peak clocks through long jobs that throttle air-cooled systems.

Higher rack density

Liquid cooling concentrates more accelerated compute per rack and improves overall facility efficiency.

1:1 GPU-to-NIC fabric

A dedicated NIC per GPU enables full-bandwidth RDMA scale-out across nodes.

Typical Business Use Cases

1

Multi-day foundation and large-model training

2

Dense liquid-cooled training rack build-outs

3

Distributed training over GPUDirect RDMA

4

High-throughput ROCm HPC workloads

Industry Applications

AI & Machine LearningHPCHigher Education & ResearchSaaS & SoftwareTelecom

Technical Overview

Based on the Supermicro AS-8125GS-TNMR2 8U platform with eight MI300X OAM accelerators on a direct-to-chip liquid cooling loop and 4th-gen AMD Infinity Fabric for all-to-all GPU links. Dual AMD EPYC 9004 CPUs, up to 6TB of DDR5, and a 1:1 GPU:NIC topology drive distributed-training bandwidth.

Accelerator8x AMD Instinct MI300X OAM, 192GB HBM3 each (1.5TB total)
GPU InterconnectAMD Infinity Fabric, all-to-all (6.4TB/s bisection)
CPUDual AMD EPYC 9004 (Genoa)
System MemoryUp to 6TB DDR5 (24 DIMM slots)
Storage16x hot-swap NVMe + 2x SATA + 2x M.2 NVMe
Networking/Fabric8x NICs, 1:1 GPU:NIC for 400G RDMA scale-out
CoolingDirect-to-chip (DLC) liquid cooling
Form Factor8U rackmount
WarrantyNexus-managed OEM warranty (configurable term)

Specifications are indicative and configured to each engagement. Request a quote for a configuration tailored to your requirements.

Warranty, Support & Fulfillment

Every system ships from an authorized channel, configured and tested, with the documentation enterprise buyers need — backed by warranty and a dedicated account team.

Enterprise Warranty

Full manufacturer warranty with optional on-site, next-business-day support and extended coverage.

Authorized Channel

Sourced through Tier-1 distribution and OEM partners — never grey market. Asset & warranty records included.

Lead Time & Deployment

48-hour quotes, then configured, burn-in tested, and delivered on a committed schedule.

Nationwide Fulfillment

Coordinated logistics, rack-and-stack, and delivery wherever your infrastructure lives.

Frequently Asked Questions

What facility support does liquid cooling require?

Direct-to-chip cooling needs facility coolant distribution (CDU and manifolds) and a rear-door or rack loop. We assess your data center and specify the CDU, flow, and redundancy as part of scoping.

Why liquid-cool MI300X instead of air?

At eight 750W accelerators per node, liquid cooling sustains higher clocks and rack density on long training runs. Air-cooled options like the Dell XE9680 suit facilities without liquid infrastructure.

Can multiple nodes form a training cluster?

Yes. The 1:1 GPU-to-NIC design supports 8-rail RDMA fabrics for multi-node scale-out. We design the fabric to your node count and growth plan.

Hardware Assistance

Configure the Supermicro AS-8125GS-TNMR2 — 8x MI300X Liquid-Cooled (EPYC 9004) with Nexus Compute

Tell us your requirements and a hardware specialist will help you specify, configure, and quote the right system — typically within two business days. No obligation.